Vaccine Protocols

Information and templates for writing a vaccine administration order, also called a protocol.

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On this page:

Guidance documents

• Guidance for Adopting Vaccine Protocols (PDF)
  Information on why vaccine protocols are necessary, why there are so many protocols, annual signing of protocols, and how to get started.
• AAP: Recommended Child and Adolescent Immunization Schedule for Ages 18 Years or Younger (PDF)
• AAFP: Adults 19 and Older Immunization Schedule
• Institute for Vaccine Safety: Excipients in Routinely Recommended Vaccines
  List of all ingredients included in U.S. vaccines, by vaccine, to help determine potential allergens.

Supporting resources

• ACOG: Recommended Maternal Vaccines infographic (PDF)
  Summary of routinely recommended maternal vaccines.
• Immunize.org: Guide to Contraindications and Precautions to Commonly Used Vaccines (PDF)
  Guide designed to help immunization providers determine what common symptoms and conditions should contraindicate vaccination and which ones should not.
• CDC: Timing and Spacing of Immunobiologics
  Vaccination providers should adhere to recommended vaccination schedules.

Vaccine protocol templates

Vaccine protocol templates to be filled in and used.

COVID-19

• 2025-26 Moderna COVID-19 Vaccine Protocol for Age 6 Months through 4 Years (Word) Updated 09/23/25
• 2025-26 COVID-19 Vaccine Protocol for Age 5 to 11 Years (Word) Updated 09/23/25
• 2025-26 COVID-19 Vaccine Protocol for Age 12 Years and Older (Word) Updated 09/23/25

DTaP

• Diphtheria, Tetanus, and Pertussis (DTaP) Routine and Catch-up Vaccine Protocol (Word) Updated 03/26/24

DTap-IPV

• Combination Diphtheria, Tetanus, and Pertussis - Polio (DTap-IPV) Vaccine Protocol (Word) Updated 03/26/24

DTaP-IPV-Hep B

• Combination Diphtheria, Tetanus, and Pertussis - Polio - Hepatitis B (DTaP-IPV-HepB) Routine and Catch-up Vaccine Protocol (Word) Updated 03/26/24

DTap-IPV-Hib

• Combination Diphtheria, Tetanus, and Pertussis - Polio - Haemophilus influenza, Type B (DTap-IPV-Hib) Routine and Catch-up Vaccine Protocol (Word) Updated 03/26/24

DTaP-IPV-Hib-Hep B

• Combination Diphtheria, Tetanus and Pertussis – Polio – Haemophilus influenza, type B – Hepatitis B (DTaP-IPV-Hib-HepB) Routine and Catch-up Vaccine Protocol (Word) Updated 03/26/24

Hepatitis A

• Hepatitis A (Hep A) Routine, Catch-up and At-risk Vaccine Protocol (Word) Updated 06/06/23

Hepatitis A and Hepatitis B (Twinrix)

• Hepatitis A and Hepatitis B as Twinrix Vaccine Protocol (Word) Updated 12/17/24

Hepatitis B

• Hepatitis B (Hep B) Routine Infant Vaccine Protocol (Word) Updated 06/06/23
• Hepatitis B (Hep B) Catch-up Vaccine Protocol (Word) Updated 12/17/24
• Hepatitis B (Hep B) Adult Vaccine Protocol (Word) Updated 12/17/24

Hib

• Haemophilus Influenza, Type B (Hib) Routine and Catch-up Vaccine Protocol (Word) Updated 06/06/23

HPV

• Human Papillomavirus Routine and Catch-up Vaccine Protocol (Word) Updated 06/06/23

Influenza

• Inactivated Influenza Vaccine (IIV) Protocol Children Age 6 Months Through 8 Years (Word) Updated 08/28/25
• Inactivated Influenza Vaccine (IIV) Protocol Persons Age 9 Years and Older (Word) Updated 08/28/25
• Live Attenuated Influenza Vaccine (LAIV) Vaccine Protocol (Word) Updated 08/28/25

Meningococcal

• Meningococcal B Vaccine Protocol (Word) Updated 11/05/24
• Meningococcal ABCWY Vaccine Protocol (Word) Updated 07/29/25
• Meningococcal Conjugate Vaccine, 4-Valent (MCV4) for Routine, Catch-up, At-risk and Booster Dose Vaccine Protocol (Word) Updated 06/06/23

MMR and MMRV

• MMR Routine and Catch-up Vaccine Protocol (Word) Updated 06/03/25
• Combination Measles, Mumps, Rubella, and Varicella (MMRV) Routine and Catch-up Vaccine Protocol (Word) Updated 06/06/23

Orthopox (mpox)

• Orthopox Vaccine Protocol: JYNNEOS Updated 08/26/24

Pneumococcal

• Pneumococcal Conjugate, 15-valent (PCV15) Routine, Catch-up & At-Risk Vaccine Protocol for Persons 6 Weeks to Age 18 Years (Word) Updated 02/20/25
• Pneumococcal Conjugate Vaccine, 15-Valent (PCV15) Vaccination: Vaccine Protocol for Persons Age 19 or Older (Word) Updated 11/05/24
• Pneumococcal Conjugate, 20-valent (PCV20) Routine, Catch-up & At-Risk Vaccine Protocol for Persons 6 Weeks to Age 18 Years (Word) Updated 09/28/23
• Pneumococcal Conjugate Vaccine, 20-Valent (PCV20) Vaccination: Vaccine Protocol for Persons Age 19 Years or Older (Word) Updated 11/05/24
• Pneumococcal Conjugate Vaccine, 21-Valent (PCV21) Vaccination: Vaccine Protocol for Persons Age 19 Years or Older (Word) Updated 11/05/24
• Pneumococcal Polysaccharide Vaccine, 23-Valent (PPSV23) Vaccination: Vaccine Protocol for Persons Age 19 Years or Older (Word) Updated 11/05/24
• Pneumococcal Polysaccharide Vaccine, 23-Valent (PPSV23) Vaccination: Vaccine Protocol for At-risk Persons Age 2-18 Years (Word) Updated 04/28/22

Polio

• Inactivated Polio Vaccine (IPV) for Routine, Catch-up and Booser Dose Vaccine Protocol (Word) Updated 04/18/24

Rotavirus

• Rotavirus Routine and Catch-up Vaccine Protocol (Word) Updated 06/06/23

RSV

• Respiratory Syncytial Virus (RSV) Monoclonal Antibody (RSV-mAb) Protocol (Word) Updated 08/28/25
• Respiratory Syncytial Virus (RSV) Vaccine Protocol (Word) Updated 08/28/25

Tdap and Td

• Tetanus and Diphtheria (Td) Vaccine Protocol for Children Less Than Age 7 with Contraindication to Pertussis-containing Vaccine (Word) Updated 03/26/24
• Tetanus and Diphtheria Toxoids and Acellular Pertussis (Tdap) and Tetanus and Diphtheria (Td) Routine, Catch-up and Booster Dose Vaccine Protocol (Word) Updated 06/06/23

Varicella and MMRV

• Varicella Routine, Catch-up and Post Exposure Prophylaxis Vaccine Protocol (Word) Updated 06/06/23
• Combination Measles, Mumps, Rubella, and Varicella (MMRV) Routine and Catch-up Vaccine Protocol (Word) Updated 06/06/23

Zoster

• Recombinant Zoster Vaccine (RZV) Routine and At-risk Vaccine Protocol (Word) Updated 06/06/23