Carbapenem Resistant Pseudomonas aeruginosa (CRPA) Information for Health Professionals

Carbapenem Resistant Pseudomonas aeruginosa (CRPA) Information for Health Professionals:
CRPA Sentinel Surveillance Case Definition and Reporting

Starting July 1, 2016 Carbapenem-Resistant Pseudomonas aeruginosa (CRPA) is reportable for residents of Hennepin and Ramsey Counties under Minnesota Rules 4605.7000 to 4605.7900.

On this page:
What to report (in Hennepin and Ramsey Counties)
How to report
Isolate submission and laboratory testing
Reporting rule change: proposal and notification letters 

What to report (in Hennepin and Ramsey Counties)

  • Pseudomonas aeruginosa isolated from any body site, that meets the following criteria:
    • Resistant to imipenem, meropenem, or doripenem based on current Clinical and Laboratory Standards Institutes Standards (CLSI) M100 standards; and/or
    • Demonstrates production of a carbapenemase by a recognized method (e.g. CarbaNP or PCR).
  • Current CLSI minimum inhibitory concentration (MIC) interpretive criteria for carbapenem-resistant Pseudomonas aeruginosa (CRPA):
Antibiotic MIC (µg/mL)
Imipenem ≥ 8
Meropenem ≥ 8
Doripenem ≥ 8

References

  • Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Fourth Informational Supplement (January 2016). CLSI document M100-S24. Wayne, Pennsylvania, 2016.

How to report

  • Yellow Disease Report Card
    CPRA may be reported using the MDH "Yellow Card."

  • Phone
    Any reportable infectious disease may be reported by phone to 651-201-5414 or 877-676-5414.

Isolate submission and laboratory testing

Reporting rule change: proposal and notification letters

Updated Tuesday, 29-Jun-2021 15:54:51 CDT